Integration of human papillomavirus types 16 and 18 in cervical adenocarcinoma.
نویسندگان
چکیده
منابع مشابه
Integration of human papillomavirus types 16 and 18 in cervical adenocarcinoma.
AIMS To determine which type of human papillomavirus (HPV) is associated with cervical adenocarcinoma and whether the virus was integrated or episomal in two continents. METHODS Biopsy specimens from the UK (n = 16) and South Africa (n = 22) were analysed by non-isotopic in situ hybridisation (NISH) for HPV types 6, 11, 16, 18, 31, 33, and 35 on archival biopsy specimens using digoxigenin lab...
متن کاملHuman papillomavirus types 16 and 18 and the prognosis of patients with stage I cervical cancer
OBJECTIVE This study sought to evaluate the prevalence of human papillomavirus (HPV) types 16 and 18 in women with clinical stage IB cervical cancer treated by radical hysterectomy with pelvic lymphadenectomy as well as to establish a correlation between HPV type and cancer prognosis. METHODS A single-center cohort study was conducted with 86 patients who had undergone radical hysterectomy fo...
متن کاملIntegration of human papillomavirus type 16 in cervical cancer cells
Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the status of HPV integration in two types of cervical pathology - invasive and non inv...
متن کاملPresence of Human Papillomavirus -16 and -18 Among Women with Breast Cancer in Isfahan Province
Background: Various studies proposed virus infection is to be a possible cause of human breast cancer. However, the data argue the association between virus and cancer are inconsistent. This study was conducted to detect whether HPV-DNA is present in tissue samples of breast cancer in Isfahan province. Materials and Methods: Paraffin embedded formalin fixed specimens were prepared from 40 brea...
متن کاملMethylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions
High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The objective of the present study was to analyze HPV L1 gene methylation and to compare the use of quantitative polymerase chain reaction (qPCR), in situ hybridization (ISH) and...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1992
ISSN: 0021-9746
DOI: 10.1136/jcp.45.5.382